Who is sponsoring NCT01931332?

NCT01931332 is sponsored by Royal Devon and Exeter NHS Foundation Trust.

What condition does NCT01931332 study?

NCT01931332 studies Osteoarthritis.

What drugs are being tested in NCT01931332?

Interventions: Femoral Nerve Block with levobupivicaine, Intrathecal injection of diamorphine.

What is the status of NCT01931332?

NCT01931332 is currently COMPLETED.

Last reviewed 2013-08-26 · How we verify

Randomised, Observer Blinded, Controlled Trial of Intrathecal Diamorphine Versus Femoral Nerve Block for Post-operative Analgesia Following Primary Total Knee Arthroplasty

NCT01931332 NA COMPLETED

Primary total knee arthroplasty (TKA) is commonly associated with moderate to severe early post-operative pain. The primary aim of this study was to investigate the impact of either a single-shot femoral nerve block (FNB) or intrathecal diamorphine (ID) on post-operative pain after TKA The Null Hypothesis is that there is no difference in the post operative pain relief provided for TKA by a single-shot femoral nerve block (FNB) as compared to intrathecal diamorphine (ID).

Details

Lead sponsor	Royal Devon and Exeter NHS Foundation Trust
Phase	NA
Status	COMPLETED
Enrolment	120
Start date	2010-02
Completion	2012-07

Conditions

Osteoarthritis

Interventions

Femoral Nerve Block with levobupivicaine
Intrathecal injection of diamorphine

Primary outcomes

Median pain score (NRS: see below) at rest — Over 72 hours post operatively
Numerical rating scale (NRS) score (where 0 = no pain and 10 = worst possible pain) assessed at times 3, 6, 12, 24, 48 and 72 hrs postoperatively.

Countries

United Kingdom