NCT01920126 is a Phase 4 clinical trial of sodium bicarbonate in Acute Kidney Injury, sponsored by Yonsei University.

Who is sponsoring NCT01920126?

NCT01920126 is sponsored by Yonsei University.

What drugs are being tested in NCT01920126?

Interventions in NCT01920126: sodium bicarbonate, Saline.

What condition does NCT01920126 study?

NCT01920126 studies Acute Kidney Injury.

Is NCT01920126 still recruiting?

NCT01920126 is currently completed. Last updated 17 July 2018.

Last reviewed 2018-07-17 · How we verify

NCT01920126

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of Sodium Bicarbonate on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery

Completed Phase 4 Last updated 17 July 2018

What this trial tests

Phase 4 trial testing sodium bicarbonate in Acute Kidney Injury in 70 participants. Completed in 23 August 2016.

Timeline

13 August 2013

Primary endpoint
23 August 2016

23 August 2016

Quick facts

Lead sponsor	Yonsei University
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	70
Start date	13 August 2013
Primary completion	23 August 2016
Estimated completion	23 August 2016
Sites	1 location across South Korea

Drugs / interventions tested

sodium bicarbonate (Sodium Bicarbonate) — full drug profile →
Saline

Conditions studied

Acute Kidney Injury — all drugs for Acute Kidney Injury →

Sponsor

Yonsei University

Who can join

Adults 20 to 90, any sex, with Acute Kidney Injury. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of study is to test whether perioperative sodium bicarbonate infusion can prevent acute kidney injury following open heart surgery in infective endocarditis patients.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effect of perioperative sodium bicarbonate administration on renal function following cardiac surgery for infective endocarditis: a randomized, placebo-controlled trial.
Cho JS, Soh S, Shim JK, Kang S, et al · · 2017 · cited 9× · PMID 28057030 · DOI 10.1186/s13054-016-1591-z

Verify or expand the search:

Other trials of sodium bicarbonate

Trials testing the same drug.

NCT04953013 — Risk Potential for Organ Dysfunction Associated With Sodium Bicarbonate Therapy (SBT) in Critically Ill Patients · completed
NCT03628430 — Effect of Buffered Lidocaine With Epinephrine in Local Anesthesia · NA · completed
NCT02647892 — Optimal Lidocaine Buffering to Reduce Injection Pain in Local Anesthesia · Phase 4 · terminated
NCT01840241 — Effect of Sodium Bicarbonate on Prevention of Acute Kidney Injury in High Risk Patients Undergoing Off-pump Coronary Art · NA · completed

Other recruiting trials for Acute Kidney Injury

Currently open trials in the same condition.

NCT07273838 — Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome · Phase 2 · recruiting
NCT07262320 — Epidemiology and Processes of Care for Renal Replacement Therapy in Acute Kidney Injury in Latin America · recruiting
NCT07351149 — Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery · recruiting
NCT07215702 — A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kid · Phase 2 · recruiting
NCT06654193 — Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury · Phase 1, PHASE2 · recruiting

Other Yonsei University trials

Trials by the same sponsor.

NCT07547592 — Gemcitabine and Docetaxel With or Without Bevacizumab (Onbevzi) for Soft Tissue Sarcoma · Phase 2 · not yet recruiting
NCT07524101 — Moderate-Intensity Statin Plus Ezetimibe in CKD and ASCVD · NA · not yet recruiting
NCT07506629 — Adductor Canal Block Methods in Bilateral Total Knee Arthroplasty · NA · not yet recruiting
NCT07515716 — Effects of High Flow Humidified Oxygen on Umbilical Artery Acid-base Balance in Cesarean Section Under Spinal Anesthesia · NA · not yet recruiting
NCT07507188 — Collaborative Clinical-translational Cohort of Amivantamab Plus Lazertinib and Amivantamab Plus Chemotherapy in Patients · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01920126 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Yonsei University
Last refreshed: 17 July 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01920126.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing