NCT01909739 is a NA clinical trial of atrovastatin in Acute Kidney Injury, sponsored by Yonsei University.

Who is sponsoring NCT01909739?

NCT01909739 is sponsored by Yonsei University.

What drugs are being tested in NCT01909739?

Interventions in NCT01909739: atrovastatin, Placebo.

What condition does NCT01909739 study?

NCT01909739 studies Acute Kidney Injury.

Is NCT01909739 still recruiting?

NCT01909739 is currently completed. Last updated 27 March 2019.

Last reviewed 2019-03-27 · How we verify

NCT01909739

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effects of Statin on Postoperative Renal Function in Valvular Heart Surgery: a Randomized, Placebo-controlled Study

Completed NA Last updated 27 March 2019

What this trial tests

NA trial testing atrovastatin in Acute Kidney Injury in 200 participants. Completed in 21 August 2015.

Timeline

1 July 2013

Primary endpoint
21 August 2015

21 August 2015

Quick facts

Lead sponsor	Yonsei University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	200
Start date	1 July 2013
Primary completion	21 August 2015
Estimated completion	21 August 2015
Sites	1 location across South Korea

Drugs / interventions tested

atrovastatin — full drug profile →
Placebo

Conditions studied

Acute Kidney Injury — all drugs for Acute Kidney Injury →

Sponsor

Yonsei University

Who can join

20 and older, any sex, with Acute Kidney Injury. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Comparison of postoperative renal function with or without statin in patients undergoing valvular heart surgery
Time frame: renal function change from 24-hour after surgery to 120-hour after surery
BUN/Cr cystatin C eGFR urine output incidence of acute kidney injury(based on the AKIN criteria)

Sponsor's own description

The aim of this study is to examine the association between preoperative statin treatment and the incidence of postoperative acute kidney injury(AKI) in patients undergoing valvular heart surgery.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Effect of atorvastatin on the incidence of acute kidney injury following valvular heart surgery: a randomized, placebo-controlled trial.
Park JH, Shim JK, Song JW, Soh S, et al · · 2016 · cited 52× · PMID 27120082 · DOI 10.1007/s00134-016-4358-8
Preoperative statin therapy for adults undergoing cardiac surgery.
Marques Antunes M, Nunes-Ferreira A, Duarte GS, Gouveia E Melo R, et al · · 2024 · cited 2× · PMID 39037762 · DOI 10.1002/14651858.cd008493.pub5

Verify or expand the search:

Other recruiting trials for Acute Kidney Injury

Currently open trials in the same condition.

NCT07273838 — Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome · Phase 2 · recruiting
NCT07262320 — Epidemiology and Processes of Care for Renal Replacement Therapy in Acute Kidney Injury in Latin America · recruiting
NCT07351149 — Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery · recruiting
NCT07215702 — A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kid · Phase 2 · recruiting
NCT06654193 — Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury · Phase 1, PHASE2 · recruiting

Other Yonsei University trials

Trials by the same sponsor.

NCT07547592 — Gemcitabine and Docetaxel With or Without Bevacizumab (Onbevzi) for Soft Tissue Sarcoma · Phase 2 · not yet recruiting
NCT07524101 — Moderate-Intensity Statin Plus Ezetimibe in CKD and ASCVD · NA · not yet recruiting
NCT07506629 — Adductor Canal Block Methods in Bilateral Total Knee Arthroplasty · NA · not yet recruiting
NCT07515716 — Effects of High Flow Humidified Oxygen on Umbilical Artery Acid-base Balance in Cesarean Section Under Spinal Anesthesia · NA · not yet recruiting
NCT07507188 — Collaborative Clinical-translational Cohort of Amivantamab Plus Lazertinib and Amivantamab Plus Chemotherapy in Patients · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01909739 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Yonsei University
Last refreshed: 27 March 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01909739.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing