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NCT01865565
Surgery for Locally Unresectable Advanced GISTs Without Metastasis After Imatinib Therapy
trial in Gastrointestinal Stromal Tumor in 51 participants. Completed in 31 December 2017.
31 December 2016
Quick facts
| Lead sponsor | Chang Gung Memorial Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 51 |
| Start date | 1 January 2013 |
| Primary completion | 31 December 2016 |
| Estimated completion | 31 December 2017 |
| Sites | 1 location across Taiwan |
Conditions studied
- Gastrointestinal Stromal Tumor — all drugs for Gastrointestinal Stromal Tumor →
Sponsor
Chang Gung Memorial Hospital
Who can join
18 and older, any sex, with Gastrointestinal Stromal Tumor. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Gastrointestinal stromal tumors (GISTs) are a form of sarcoma and the most common sarcoma tumors of the gastrointestinal tract. The limited clinical experience suggests that GIST patients may benefit from neo-adjuvant therapy from primary GIST. This is a prospective, multicenter, open, observational study in evaluation of safety and efficacy of imatinib compared with that of historical data for locally unresectable advanced GIST without metastasis. The study will include an up to 28-day screening period, followed by receiving imatinib mesylate (400 mg/day) for at least 6-12 months and followed up for 3 years after surgery.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Prospective Evaluation of Neoadjuvant Imatinib Use in Locally Advanced Gastrointestinal Stromal Tumors: Emphasis on the Optimal Duration of Neoadjuvant Imatinib Use, Safety, and Oncological Outcome.
Wang SY, Wu CE, Lai CC, Chen JS, et al · · 2019 · cited 23× · PMID 30934606 · DOI 10.3390/cancers11030424 -
Surgical treatment of gastrointestinal stromal tumors of the stomach: current status and future perspective.
Lim KT. · · 2017 · cited 9× · PMID 29354761 · DOI 10.21037/tgh.2017.12.01
Verify or expand the search:
- PubMed search for NCT01865565
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
Other recruiting trials for Gastrointestinal Stromal Tumor
Currently open trials in the same condition.
- NCT04933669 — Prospective Multicenter Clinical Study of Neoadjuvant Imatinib Mesylate for Gastrointestinal Stromal Tumors · Phase 2 · recruiting
- NCT02834013 — Nivolumab and Ipilimumab in Treating Patients With Rare Tumors · Phase 2 · active not recruiting
- NCT00265798 — Sorafenib in Treating Patients With Malignant Gastrointestinal Stromal Tumor That Progressed During or After Previous Tr · Phase 2 · active not recruiting
Other Chang Gung Memorial Hospital trials
Trials by the same sponsor.
- NCT07419789 — Precision Care for Older Persons · NA · not yet recruiting
- NCT07248345 — Virtual Reality Intervention for Family Caregivers of Persons Living With Dementia · NA · not yet recruiting
- NCT07036978 — Metabolomic and Immune-Microbiome Profiling for Unresectable Pancreatic Cancer · not yet recruiting
- NCT07489833 — Metabolomic Pathways and Traditional Chinese Medicine Body Constitution in Cancer-related Fatigue · not yet recruiting
- NCT07496528 — The ACURE Trial: Acupuncture for Colorectal Recovery · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01865565 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chang Gung Memorial Hospital
- Last refreshed: 9 August 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01865565.
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