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Ramipril for the Treatment of Oligospermia: A Double-Blind Randomized Control Trial
This is a randomized controlled trial to evaluate the effect of ramipril in stimulating and promoting sperm production in men with low sperm count. Ramipril is an Angiotensin Converting Enzyme Inhibitor (ACEI) currently used to treat high blood pressure. However, previous studies have shown that this class of medications can improve sperm parameters. The purpose of this study is to evaluate the efficacy of ramipril compared to placebo (Substance That is not known to have treatment effect), in improving sperm density in infertile men with documented low sperm count. This study will help us identify subjects that might benefit from treatment with this medication, and the effect it will have on sperm count, shape, and motility.
Details
| Lead sponsor | Weill Medical College of Cornell University |
|---|---|
| Phase | NA |
| Status | TERMINATED |
| Enrolment | 2 |
| Start date | 2013-07 |
| Completion | 2016-06 |
Conditions
- Oligospermia
- Teratospermia
- Asthenozoospermia
- Male Infertility
Interventions
- Ramipril
- Placebo
Primary outcomes
- Sperm Density in Infertile Men With Documented Oligospermia. — 32 weeks
Countries
United States