Who is sponsoring NCT01800370?

NCT01800370 is sponsored by Mayo Clinic.

What drugs are being tested in NCT01800370?

Interventions: Hyperglycemia, Saline, Exercise, Blood Draws, Fasting procedure.

What is the status of NCT01800370?

NCT01800370 is currently COMPLETED.

Last reviewed 2014-05-09 · How we verify

The Effect of Mixed Exercise and Metabolic Stress Upon Pituitary Secretion in Relationship to Age in Healthy Men: a Pilot Study

NCT01800370 Phase 1 COMPLETED

Aging in men reduces the amount of luteinizing hormone (LH) and testosterone (Te) secreted in each burst. Stress-associated mechanisms introduced by acute illness and chronic disease decrease LH and Te secretion further. A major unresolved issue is whether the aging process heightens the negative effects of a stressor (whether physical or metabolic) upon LH and Te secretion. This study will assess LH and Te secretion in response to a physical stressor (maximal exercise) and a common metabolic stressor (hyperglycemia) as a function of age in healthy men ages 18-80 yr.

Details

Lead sponsor	Mayo Clinic
Phase	Phase 1
Status	COMPLETED
Enrolment	40
Start date	2013-02
Completion	2014-04

Conditions

Healthy

Interventions

Hyperglycemia
Saline
Exercise
Blood Draws
Fasting procedure

Primary outcomes

Change in Testosterone concentration after 30 minutes of exercise — 30 minutes after initiating exercise
During the exercise visit subjects will perform an exercise test on a bike and lift weights with both arms for a total of 30 minutes.

Countries

United States