NCT01784562 (EAS) is a clinical trial of Adempas (Riociguat, BAY63-2521) in Hypertension, Pulmonary, sponsored by Bayer.

Who is sponsoring NCT01784562?

NCT01784562 is sponsored by Bayer.

What drugs are being tested in NCT01784562?

Interventions in NCT01784562: Adempas (Riociguat, BAY63-2521).

What condition does NCT01784562 study?

NCT01784562 studies Hypertension, Pulmonary.

Is NCT01784562 still recruiting?

NCT01784562 is currently no longer available. Last updated 6 January 2016.

Last reviewed 2016-01-06 · How we verify

NCT01784562: EAS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Riociguat in Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH)

NO LONGER AVAILABLE Last updated 6 January 2016

What this trial tests

trial testing Adempas (Riociguat, BAY63-2521) in Hypertension, Pulmonary. No longer available.

Quick facts

Lead sponsor	Bayer
Status	NO LONGER AVAILABLE
Study type	EXPANDED_ACCESS
Sites	102 locations across Italy, Colombia, Japan, Denmark, Netherlands, Russia, Belgium, Sweden

Drugs / interventions tested

Adempas (Riociguat, BAY63-2521) — full drug profile →

Conditions studied

Hypertension, Pulmonary — all drugs for Hypertension, Pulmonary →

Sponsor

Bayer — full company profile →

Who can join

Adults 18 to 80, any sex, with Hypertension, Pulmonary. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to assess safety, tolerability and clinical effects of different doses of riociguat in patients with inoperable Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and who are not satisfactorily treated and cannot participate in any other CTEPH trial. In the US the study runs as an Expanded Access program under 21 CFR 312.320.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Riociguat in patients with chronic thromboembolic pulmonary hypertension: results from an early access study.
McLaughlin VV, Jansa P, Nielsen-Kudsk JE, Halank M, et al · · 2017 · cited 18× · PMID 29282032 · DOI 10.1186/s12890-017-0563-7

Verify or expand the search:

Other trials of Adempas (Riociguat, BAY63-2521)

Trials testing the same drug.

NCT02759419 — A Long-term Extension Study of Riociguat in Patients With Symptomatic Pulmonary Arterial Hypertension. · Phase 4 · completed

Other recruiting trials for Hypertension, Pulmonary

Currently open trials in the same condition.

NCT07087613 — Deep Learning Detection of Pulmonary Hypertension and Low Ejection Fraction Via Digital Stethoscope and 3-Lead ECG · recruiting
NCT06814145 — Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023) · Phase 2 · recruiting
NCT05867914 — Early Feasibility Study Evaluating the 3P-100 Device in Subjects With PH-ILD · NA · active not recruiting
NCT05719415 — Functional Pulmonary Capillary Surface Area in BPA for CTEPH · NA · recruiting
NCT05179876 — A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no O · Phase 3 · recruiting

Other Bayer trials

Trials by the same sponsor.

NCT05900388 — A Study to Observe the Pattern of Use and Safety of Rivaroxaban in Children Under 2 Years Old With Venous Thromboembolis · not yet recruiting
NCT07490431 — An Observational Study to Learn More About How Elinzanetant is Used and How Well it Works for Women With Menopause Sympt · not yet recruiting
NCT05477953 — An Observational Pregnancy Safety Study in Women Who Were Exposed to the Drug Nifurtimox During Pregnancy to Learn About · not yet recruiting
NCT07192952 — A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Child · Phase 3 · not yet recruiting
NCT07450599 — A Study to Learn How Well a Combination of Darolutamide and Androgen Deprivation Therapy (ADT) Works as a Treatment Befo · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01784562 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Bayer
Last refreshed: 6 January 2016

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01784562.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing