Nerve Grafting With an Allograft During Radical Prostatectomy - Extended Follow-up in a Prospective Randomized Trial

NCT01770340 Phase 4 TERMINATED

Earlier studies were able to show that an improvement of the erectile function following a non-nerve sparing radical prostatectomy could be achieved using an autologous nerve graft. The investigators evaluate the use of the implantation of the allogenic nerve graft Avance® in patients undergoing non nerve-sparing radical prostatectomy.

Details

Lead sponsor	Kantonsspital Winterthur KSW
Phase	Phase 4
Status	TERMINATED
Enrolment	30
Start date	2011-01
Completion	2020-07-01

Conditions

• Erectile Dysfunction Following Radical Prostatectomy

Interventions

• Radical prostatectomy with implantation of allograft
• Radical prostatectomy without implantation of allograft

Primary outcomes

• Erectile function score (IIEF: international index of erectile function) after non nerve sparing radical prostatectomy — 24 months
  Erectile function score (IIEF: international index of erectile function) after non nerve sparing radical prostatectomy. To show a complete impotence in the control group and an enhancement of the initial postoperative impotence in the treatment group

Countries

Switzerland