Last reviewed · How we verify
NCT01764230: OVARONKO
Prevention of Ovarian Function Damage by a GnRH Analogue During Chemotherapy in Hodgkin Lymphoma Patients
NA trial testing triptorelin in Hodgkin Lymphoma in 72 participants. Completed in 1 January 2008.
1 July 2007
Quick facts
| Lead sponsor | Masaryk University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 72 |
| Start date | 1 January 2004 |
| Primary completion | 1 July 2007 |
| Estimated completion | 1 January 2008 |
| Sites | 1 location across Czechia |
Drugs / interventions tested
- triptorelin (triptorelin) — full drug profile →
Conditions studied
- Hodgkin Lymphoma — all drugs for Hodgkin Lymphoma →
- Hodgkin Disease — all drugs for Hodgkin Disease →
Sponsor
Masaryk University
Who can join
Adults 18 to 35, female only, with Hodgkin Lymphoma or Hodgkin Disease. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Premature ovarian failure after chemotherapy
Time frame: 6 months after the end of chemotherapy
Premature ovarian failure defined as levels of FSH over 15 IU/l in peripheral blood. -
Premature ovarian failure after chemotherapy
Time frame: 12 months after the end of chemotherapy
Premature ovarian failure defined as levels of FSH over 15 IU/l in peripheral blood.
Sponsor's own description
Chemotherapy as one of the basic modalities of oncology treatment often leaves permanent implications and among the most common is infertility as a result of irreversible gonadal damage. This project sets the primary target to verify the protective effect GnRH analogues administration to protect ovarian tissue during three different regimens of chemotherapy in patients with Hodgkin disease (HD) in reproductive age.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT01764230
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of triptorelin
Trials testing the same drug.
- NCT05701007 — Real World Evidence Study on Metastatic Prostate Cancer in the Pirkanmaa Hospital District in Finland · completed
- NCT02278185 — Enzalutamide Versus Standard Androgen Deprivation Therapy for the Treatment Hormone Sensitive Prostate Cancer · Phase 2 · completed
- NCT00066703 — Triptorelin With Either Exemestane or Tamoxifen in Treating Premenopausal Women With Hormone-Responsive Breast Cancer · Phase 3 · completed
Other recruiting trials for Hodgkin Lymphoma
Currently open trials in the same condition.
- NCT07020533 — A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Pa · Phase 1 · recruiting
- NCT07566377 — Cord Blood Transplantation in Children and Young Adults With Blood Cancer · Phase 2 · recruiting
- NCT07285044 — The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Tr · Phase 2 · recruiting
- NCT06176690 — Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas · Phase 1 · recruiting
- NCT07002216 — BrECADD Therapy in Stage 2 B-IV Hodgkin Lymphoma · Phase 2 · recruiting
Other Masaryk University trials
Trials by the same sponsor.
- NCT07019727 — ESSKA/ESMA ACL Injury Prevention Program in Czech Sport · NA · recruiting
- NCT07085247 — The Role of Cutibacterium Acnes in the Development of Degenerative Lumbar Intervertebral Disc Disease · recruiting
- NCT06887179 — Point-of-Care Ultrasound in Chronic Heart Failure · NA · not yet recruiting
- NCT06906614 — Psychophysiological Stress Response in Medical Students During Simulation-Based Communication Training -Study Protocol · not yet recruiting
- NCT06426030 — Validation of Czech Language Versions of Questionnaires for ALS Patients' Functional Status and Biomarker Long-term Foll · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01764230 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Masaryk University
- Last refreshed: 7 January 2013
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01764230.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing