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NCT01762813: ACROBATICC

Assessment of Clinically Related Outcomes and Biomarker Analysis for Translational Integration in Colorectal Cancer

Recruiting now Last updated 24 July 2024
What this trial tests

trial testing open and laparoscopic surgery in Colorectal Cancer in 1,200 participants. Currently enrolling.

Timeline
1 January 2013
Primary endpoint
31 December 2027
31 December 2027

Quick facts

Lead sponsorHelse Stavanger HF
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment1,200
Start date1 January 2013
Primary completion31 December 2027
Estimated completion31 December 2027
Sites1 location across Norway

Drugs / interventions tested

Conditions studied

Sponsor

Helse Stavanger HF — full company profile →

Who can join

18 and older, any sex, with Colorectal Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

* A prospective, observational study on clinical outcomes of surgical management of primary and metastatic colorectal cancer * Prospective collection of tissues to explore potential biomarkers in blood and/or primary or secondary cancers and/or normal colon

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Prevalence of PD-L1 expression is associated with EMAST, density of peritumoral T-cells and recurrence-free survival in operable non-metastatic colorectal cancer.
    Watson MM, Lea D, Gudlaugsson E, Skaland I, et al · · 2020 · cited 17× · PMID 32314040 · DOI 10.1007/s00262-020-02573-0
  2. Assessment of clinically related outcomes and biomarker analysis for translational integration in colorectal cancer (ACROBATICC): study protocol for a population-based, consecutive cohort of surgically treated colorectal cancers and resected colorectal liver metastasis.
    Søreide K, Watson MM, Lea D, Nordgård O, et al · · 2016 · cited 13× · PMID 27357108 · DOI 10.1186/s12967-016-0951-4
  3. A template to quantify the location and density of CD3 + and CD8 + tumor-infiltrating lymphocytes in colon cancer by digital pathology on whole slides for an objective, standardized immune score assessment.
    Lea D, Watson M, Skaland I, Hagland HR, et al · · 2021 · cited 12× · PMID 33439293 · DOI 10.1007/s00262-020-02834-y
  4. Elevated Microsatellite Alterations at Selected Tetranucleotides (EMAST) Is Not Attributed to MSH3 Loss in Stage I-III Colon cancer: An Automated, Digitalized Assessment by Immunohistochemistry of Whole Slides and Hot Spots.
    Watson MM, Lea D, Hagland HR, Søreide K. · · 2019 · cited 9× · PMID 31677491 · DOI 10.1016/j.tranon.2019.08.009
  5. Neoadjuvant Immunotherapy Followed by Surgery Compared with Upfront Surgery Alone in Operable Colon Cancer with Deficient Mismatch Repair: Modeling Oncological Outcomes and Numbers Needed to Treat.
    Kanani A, Veen T, Lea D, Zaharia C, et al · · 2025 · cited 2× · PMID 39738901 · DOI 10.1245/s10434-024-16755-y
  6. Pre- and postoperative expression of circulating CEACAM1 and CEACAM6 using a nanoparticle-supported, lectin-specific assay detected in serum from patients with colorectal cancer.
    Kanani A, Alexeeva M, Vinod R, Pettersson K, et al · · 2026 · PMID 42017600 · DOI 10.1080/00365521.2026.2661974

Verify or expand the search:

Other recruiting trials for Colorectal Cancer

Currently open trials in the same condition.

Other Helse Stavanger HF trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01762813.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing