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NCT01754298
Study of Two Surgical Drilling Techniques to Treat Juvenile Osteochondritis Dissecans of the Knee
NA trial testing Retro-articular drilling in Juvenile Osteochondritis Dissecans in 91 participants. Completed in 16 October 2020.
29 July 2019
Quick facts
| Lead sponsor | Boston Children's Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 91 |
| Start date | 18 January 2013 |
| Primary completion | 29 July 2019 |
| Estimated completion | 16 October 2020 |
| Sites | 14 locations across Canada, United States |
Drugs / interventions tested
- Retro-articular drilling
- Trans-articular drilling
Conditions studied
- Juvenile Osteochondritis Dissecans — all drugs for Juvenile Osteochondritis Dissecans →
Sponsor
Boston Children's Hospital
Who can join
Adults 8 to 18, any sex, with Juvenile Osteochondritis Dissecans. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to compare the functional, clinical and radiographic outcomes associated with trans-articular drilling versus retro-articular drilling, two commonly employed techniques of operative treatment for stable forms of juvenile osteochondritis dissecans (JOCD) lesions. This study also aims to better define the natural history of this condition in its most commonly identified pathological state (as a stable lesion) following surgical intervention by determining the rate of radiographic healing and any need for secondary surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Transarticular Versus Retroarticular Drilling of Stable Osteochondritis Dissecans of the Knee: A Prospective Multicenter Randomized Controlled Trial by the ROCK Group.
Heyworth BE, Ganley TJ, Liotta ES, Hergott KA, et al · · 2023 · cited 9× · PMID 37039536 · DOI 10.1177/03635465231165290
Verify or expand the search:
- PubMed search for NCT01754298
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01754298 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Boston Children's Hospital
- Last refreshed: 3 December 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01754298.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing