Abatacept as GVHD Prophylaxis Phase 2

NCT01743131 PHASE2 COMPLETED Results posted

This is a phase II multi-center, randomized, double blind, placebo-controlled trial. The investigators are doing this study to see if a new drug, abatacept, can be used together with a calcineurin inhibitor (cyclosporine or tacrolimus) and methotrexate to provide better protection against Acute Graft versus Host Disease (aGvHD) without causing more infections.

Details

Lead sponsor	Boston Children's Hospital
Phase	PHASE2
Status	COMPLETED
Enrolment	186
Start date	Fri Feb 01 2013 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Sat Mar 30 2024 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Graft vs Host Disease
• Malignancy

Interventions

• Abatacept
• placebo

Countries

Canada, United States