NCT01727258 is a NA clinical trial of Mouth Rinse in Dentin Sensitivity, sponsored by Johnson & Johnson Consumer and Personal Products Worldwide.

Who is sponsoring NCT01727258?

NCT01727258 is sponsored by Johnson & Johnson Consumer and Personal Products Worldwide.

What drugs are being tested in NCT01727258?

Interventions in NCT01727258: Mouth Rinse, Fluoride Toothpaste, Potassium Nitrate Toothpaste.

What condition does NCT01727258 study?

NCT01727258 studies Dentin Sensitivity.

Is NCT01727258 still recruiting?

NCT01727258 is currently completed. Last updated 8 June 2015.

Are results published for NCT01727258?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2015-06-08 · How we verify

NCT01727258

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of an Experimental Mouth Rinse Device for Relieving Dentinal Hypersensitivity

Completed NA Results posted Last updated 8 June 2015

What this trial tests

NA trial testing Mouth Rinse in Dentin Sensitivity in 153 participants. Completed in 1 February 2013.

Timeline

1 December 2012

Primary endpoint
1 February 2013

1 February 2013

Quick facts

Lead sponsor	Johnson & Johnson Consumer and Personal Products Worldwide
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Enrollment	153
Start date	1 December 2012
Primary completion	1 February 2013
Estimated completion	1 February 2013
Sites	1 location across United States

Drugs / interventions tested

Mouth Rinse — full drug profile →
Fluoride Toothpaste — full drug profile →
Potassium Nitrate Toothpaste

Conditions studied

Dentin Sensitivity — all drugs for Dentin Sensitivity →

Sponsor

Johnson & Johnson Consumer and Personal Products Worldwide — full company profile →

Who can join

18 and older, any sex, with Dentin Sensitivity. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Mean Tactile Sensitivity Score at Week 4
Time frame: 4 weeks
Tooth sensitivity was measured using a Yeaple probe. The force at which discomfort was felt by the participant was recorded on a scale of 10-80 grams. The score for each participant was calculated by averaging the scores for all study teeth for that participant.
Mean Tactile Sensitivity Score at Week 2
Time frame: 2 weeks
Tooth sensitivity was measured using a Yeaple probe. The force at which discomfort was felt by the participant was recorded on a scale of 10-80 grams. The score for each participant was calculated by averaging the scores for all study teeth for that participant.

Sponsor's own description

This study is for people with sensitive teeth and involves going to the dentist for 4 visits over 6 weeks. At each visit the dentist will look at the mouth, teeth, tongue and gums of subjects, and check for sensitive teeth. During the first 2 weeks, participants will brush their teeth two times a day with the fluoride toothpaste provided. Then, if they qualify to continue in the study, participants will be assigned to a treatment group. All the groups will get toothpaste currently sold on the market, and one group will get a mouthwash with an experimental ingredient to use as well. Subjects will have an equal chance of being assigned to any one of the three groups. For the next 4 weeks, subjects will use their assigned products according to the directions provided. At Visit 1 subjects will be supervised while they brush their teeth to ensure they understand the directions. They will also have supervised use of the product at Visit 2. We will see if the mouthwash helps to reduce tooth sensitivity during the study.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Dentin Sensitivity

Currently open trials in the same condition.

NCT06463938 — A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH · NA · recruiting

Other Johnson & Johnson Consumer and Personal Products Worldwide trials

Trials by the same sponsor.

NCT06798441 — Determination of the Oral Irritation Potential of a Fluoride Rinse in Children · NA · completed
NCT06479096 — Four-Week Oral Malodor and Clinical Safety for a Concentrated Cosmetic Mouthwash · NA · completed
NCT07028671 — Exploratory Investigation of Motilium's Effectiveness and Safety for the OTC Treatment of Dyspepsia-related Symptoms · completed
NCT03213353 — A Bioequivalence Study Between Two Brands of Medications to Treat Cough & Cold Symptoms · Phase 1 · completed
NCT03041064 — Multiday Beach Study · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01727258 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Johnson & Johnson Consumer and Personal Products Worldwide
Last refreshed: 8 June 2015

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01727258.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing