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Change of Airway Hyperresponsiveness to Mannitol and Methacholine During Intensified Anti-inflammatory Treatment in Patients With Asthma.
Control of airway inflammation is the cornerstone of asthma management. The aim of the present pilot study was to assess whether, and in which magnitude, a leukotriene receptor antagonist (LTRA) added to a basic treatment of inhaled corticosteroids (ICS) + long-acting betamimetics (LABA) might improve airway hyperresponsiveness and inflammation in well-controlled patients with asthma.
Details
| Lead sponsor | Cantonal Hosptal, Baselland |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 17 |
| Start date | 2007-01 |
| Completion | 2012-01 |
Conditions
- Asthma
Interventions
- montelukast
Primary outcomes
- pd15 mannitol — 4 weeks
Improvement in pd15 mannitol over a treatment period of 4 weeks.
Countries
Switzerland