Last reviewed · How we verify
The Use of Optison Echocardiography Contrast in the Detection of Left Atrial Appendage Thrombus With Transesophageal Echocardiography. (DOLOP)
The investigators intend to determine if using Optison echocardiography contrast increases sensitivity and specificity of detecting left atrial appendage thrombus in transesophageal echocardiography studies as opposed to standard 2D and 3D TEE imaging without the use of echo contrast.
Details
| Lead sponsor | University of Utah |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 100 |
| Start date | 2013-06 |
| Completion | 2018-05 |
Conditions
- Atrial Fibrillation
Interventions
- Optison echocardiography contrast agent
Primary outcomes
- Percent Confidence in Assessment of Left Atrial Appendage Thrombus — One Transesophageal Echocardiography, up to 1 hour
Confidence among echo readers to determine presence or absence of left atrial appendage thrombus before and after injection of Optison contrast agent. Percent confidence was calculated from a subjective assessment made by each reader after viewing the echo images. A six-point scale was used by the readers to grade the subjective assessment of their confidence in detecting thrombus; a score of 0 representing 0% (no confidence) up to a score of 5 representing 100% (total confidence) that the interpretation was correct for presence or absence of left atrial appendage thrombus. The reported percent confidence is the average of both echo readers.
Countries
United States