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NCT01702948
Studying Nicotine Addiction With Transcranial Magnetic Stimulation
trial in Nicotine Dependence in 46 participants. Completed in 3 October 2017.
Quick facts
| Lead sponsor | National Institute on Drug Abuse (NIDA) |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 46 |
| Start date | 10 September 2012 |
| Estimated completion | 3 October 2017 |
| Sites | 1 location across United States |
Conditions studied
- Nicotine Dependence — all drugs for Nicotine Dependence →
Sponsor
National Institute on Drug Abuse (NIDA)
Who can join
Adults 18 to 55, any sex, with Nicotine Dependence. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: \- Nicotine addiction often makes it difficult to stop smoking. Researchers want to understand the areas of the brain that are important in nicotine addiction. They will use a type of brain stimulation called repetitive transcranial magnetic stimulation (rTMS) to look at part of the brain that may be involved in nicotine addiction. They will see how these areas affect brain function, thinking, and decision making. For this study, rTMS will first be tested on nonsmokers, then smokers will be recruited at a later time. Objectives: \- To study areas of the brain involved in nicotine addiction. Eligibility: \- Individuals at least 18 years of age who do not smoke. Design: * Participants will be screened with a physical exam and medical history. They will also provide a urine sample. * There will be four study sessions. The first session will involve a magnetic resonance imaging (MRI) scan. The other three visits will involve rTMS and MRI scans. * The first MRI scan will take a baseline picture of the brain. Participants will also practice the tasks for the other three sessions in a mock scanner. * At the next three visits, participants will have rTMS and MRI scans. Two visits will involve rTMS; the other visit will involve mock rTMS with no actual magnetic stimulation. During the MRI scans, participants will perform tasks that involve decision making.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT01702948
- Europe PMC full search
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Related trials
Other recruiting trials for Nicotine Dependence
Currently open trials in the same condition.
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- NCT07250230 — Effect of Perioperative High-dose Transdermal Nicotine Patch on Pain Sensitivity Among Male Abstinent Tobacco Smokers Un · NA · recruiting
- NCT07040566 — A Trial of Varenicline for E-cigarette Cessation · Phase 2 · recruiting
- NCT07001930 — Effects of Cannabidiol on Stress and Nicotine Withdrawal · Phase 1 · recruiting
- NCT06765291 — Behavioral Intervention for Youth to Promote Vaping Cessation · NA · recruiting
Other National Institute on Drug Abuse (NIDA) trials
Trials by the same sponsor.
- NCT07468552 — Trial of Tirzepatide for the Treatment of Cannabis Use Disorder · Phase 2 · not yet recruiting
- NCT06808932 — VK4-116 Phase I Study With Food-Effect · Phase 1 · not yet recruiting
- NCT06676059 — SMART-r: Substance Monitoring and Active Relapse Tracking Repository · recruiting
- NCT06577454 — Measuring the Effects of Neurostimulation on Risky and Ambiguous Decision-Making Capacity in People With and Without Sub · NA · suspended
- NCT06868914 — Phase I Trial of High-Density Theta Burst Stimulation (hdTBS) · Phase 1 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01702948 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute on Drug Abuse (NIDA)
- Last refreshed: 5 December 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01702948.
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