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Optimal Dose of Spinal Mepivacaine Combined With Fentanyl For Knee Arthroscopy
Prolonged motor block and delayed ability to walk are limitations of spinal anesthesia in ambulatory (same-day) surgery. This can be improved by lowering the dose of local anesthetic (a medication that, when injected around nerves, blocks nerve conduction, resulting in numbness and weakness) used in the spine, but too low a dose can result in an incomplete block (inadequate anesthesia) in some patients. There is evidence that adding a low dose of fentanyl, a narcotic, to mepivacaine enhances the anesthetic effect. The purpose of this study is to determine the lowest dose of mepivacaine, a local anesthetic, when combined with fentanyl, for which spinal anesthesia is adequate for ambulatory knee arthroscopy.
Details
| Lead sponsor | Hospital for Special Surgery, New York |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 56 |
| Start date | 2011-12 |
| Completion | 2013-12 |
Conditions
- Arthroscopic Knee Surgery
Interventions
- Mepivacaine (24 mg) plus fentanyl
- Mepivacaine (27 mg) plus fentanyl
- Mepivacaine (30 mg) plus fentanyl
- Mepivacaine
Primary outcomes
- Time From Spinal Administration to Block Regression to the S1 Dermatome in Post-Anesthesia Care Unit (PACU) — Participants will be followed for the duration of their recovery after surgery in the post-anesthesia care unit (PACU), an expected average of 2-4 hours.
The time frame of the study for each patient only covers the period between time of surgery and time of discharge from the hospital, which is on the same day as the day of surgery
Countries
United States