Effect of Perioperative Topical Diclofenac on Intraocular Inflammation After Cataract Surgery and the Incidence of Postoperative Macular Edema in Patients With Diabetic Retinopathy

NCT01694212 NA COMPLETED

Diabetes has many negative effects on patients' general health. Among many other consequences it speeds up the cataract formation and that is why diabetic patients need cataract surgery very often. The known side effect of cataract surgery even in otherwise healthy patients is postoperative edema of the back of the eye (what causes decrease of vision), which has greater incidence especially in patients who have diabetic eye problems. The cause of that might be the intraocular inflammation which was previously demonstrated to be significantly more prominent in patients with untreated diabetic eye problems. Therefore we will examine if the 7 day use of anti-inflammatory eye drops prior to the cataract surgery prevent the formation of the edema of the back of the eye.

Details

Lead sponsor	Eye Clinic Medic Zuljan Jukic
Phase	NA
Status	COMPLETED
Enrolment	55
Start date	2012-10
Completion	2016-12

Conditions

• Macular Edema
• Cataract
• Diabetic Retinopathy

Interventions

• Perioperative Diclofenac eye-drops administration
• placebo

Primary outcomes

• Change of Central Macular Thickness — -7, 0, 1, 7, 30, 90 days after the cataract surger
  The central macular thickness will be measured with OCT machine.

Countries

Croatia