NCT01691716 (Tendoactive) is a NA clinical trial of Tendoactive in Achilles Tendinopathy, sponsored by Bioiberica.

Who is sponsoring NCT01691716?

NCT01691716 is sponsored by Bioiberica.

What drugs are being tested in NCT01691716?

Interventions in NCT01691716: Tendoactive, Eccentric training.

What condition does NCT01691716 study?

NCT01691716 studies Achilles Tendinopathy.

Is NCT01691716 still recruiting?

NCT01691716 is currently completed. Last updated 25 February 2014.

Last reviewed 2014-02-25 · How we verify

NCT01691716: Tendoactive

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Prospective Randomized Study Comparing the Therapeutic Effect of Tendoactive®, Eccentric Training, and a Combination of Both as a Treatment of Achilles Tendinopathy

Completed NA Last updated 25 February 2014

What this trial tests

NA trial testing Tendoactive in Achilles Tendinopathy in 100 participants. Completed in 1 September 2013.

Timeline

1 April 2012

Primary endpoint
1 June 2013

1 September 2013

Quick facts

Lead sponsor	Bioiberica
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	100
Start date	1 April 2012
Primary completion	1 June 2013
Estimated completion	1 September 2013
Sites	6 locations across Spain

Drugs / interventions tested

Tendoactive — full drug profile →
Eccentric training

Conditions studied

Achilles Tendinopathy — all drugs for Achilles Tendinopathy →

Sponsor

Bioiberica — full company profile →

Who can join

Adults 18 to 70, any sex, with Achilles Tendinopathy. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Change from Baseline in VISA-A score at 12 weeks
Time frame: 12 weeks
Functional impairment of the Achilles tendon is measured using VISA-A score. Score of patient-related outcome measure: Achilles tendon: VISA-A \[0=worse, 100=perfect\] derived from eight validated questions on pain and function during activities of daily living

Sponsor's own description

The purpose of this study is to determine whether Tendoactive, eccentric training, or the combination or both could be effective in the treatment of Achilles tendinopathy.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

A 3-Arm Randomized Trial for Achilles Tendinopathy: Eccentric Training, Eccentric Training Plus a Dietary Supplement Containing Mucopolysaccharides, or Passive Stretching Plus a Dietary Supplement Containing Mucopolysaccharides.
Balius R, Álvarez G, Baró F, Jiménez F, et al · · 2016 · cited 26× · PMID 28053674 · DOI 10.1016/j.curtheres.2016.11.001

Verify or expand the search:

Other recruiting trials for Achilles Tendinopathy

Currently open trials in the same condition.

NCT06905743 — Isometric Contraction-Based Pain Modulation Versus Eccentric Strengthening in Treating Achilles Tendinopathy · NA · active not recruiting
NCT06905756 — Comparative Effect of Accelerated Rehabilitation and Eccentric Strengthening Exercises on Patients With AT · NA · active not recruiting
NCT06639308 — Eendoscopic Versus Open Flexor Hallucis Longus Transfer in Managing Various Tendon Achilles Disorders · NA · active not recruiting
NCT07039643 — The Pilates Method in the Rehabilitation of Achilles Tendinopathy - A Randomised Controlled Study · NA · active not recruiting
NCT05464498 — Evaluation of Collagen-based Medical Device Treatment Combined With Physiotherapy in Subjects With Achilles Tendinopathy · NA · recruiting

Other Bioiberica trials

Trials by the same sponsor.

NCT05813054 — Clinical Study to Evaluate the Anti-aging Efficacy of Dermial® · NA · completed
NCT05282992 — NAtive Collagen Type II In Healthy VoluntEers With Joint Discomfort · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01691716 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Bioiberica
Last refreshed: 25 February 2014

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01691716.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing