Last reviewed · How we verify
NCT01688986
Environmental Polymorphisms Registry Health and Exposures Survey
trial in Diabetes in 9,000 participants. Completed in 22 November 2016.
Quick facts
| Lead sponsor | National Institute of Environmental Health Sciences (NIEHS) |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 9,000 |
| Start date | 25 August 2012 |
| Estimated completion | 22 November 2016 |
| Sites | 1 location across United States |
Conditions studied
- Diabetes — all drugs for Diabetes →
- Heart Disease — all drugs for Heart Disease →
- Asthma — all drugs for Asthma →
Sponsor
National Institute of Environmental Health Sciences (NIEHS)
Who can join
18 and older, any sex, with Diabetes or Heart Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The Environmental Polymorphisms Registry (EPR) Health and Exposure Survey is designed to gather health, family history of disease, environmental exposures and lifestyle data on adult EPR subjects. The EPR is a registry established to collect and store DNA samples from 20,000 volunteers from North Carolina and to serve as a resource to scientist investigating genotype-driven translational research of chronic conditions. Under this new protocol, we will administer a health and exposures survey to all EPR subjects. The information collected in the survey will be used to better characterize the EPR population thus making it more useful to NIEHS researchers. The survey contains approximately 200 questions. Data from the survey will help researchers develop hypotheses, design follow-up studies, and select appropriate subjects. The survey will be administered to EPR subjects using a modified version of the Dillman Total Design Method (TDM) for surveys. This method requires following specific time-dependent steps for survey administration that incorporate both self- and phone administration and other types of phone and mail contact. The goal of TDM is to maximize subject response rates.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
TLR5 Activation Exacerbates Airway Inflammation in Asthma.
Whitehead GS, Hussain S, Fannin R, Trempus CS, et al · · 2020 · cited 15× · PMID 32060608 · DOI 10.1007/s00408-020-00337-2
Verify or expand the search:
- PubMed search for NCT01688986
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01688986 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute of Environmental Health Sciences (NIEHS)
- Last refreshed: 31 August 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01688986.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing