Intra-nasal Ketamine for Analgesia in the Emergency Department (INKA)

NCT01686009 Phase 4 COMPLETED

The provision of analgesia to patients in pain is a fundamental necessity of emergency department practice and is usually accomplished using IV opioids. However, significant barriers exist to the provision of timely analgesia by the IV route. The use of the IN route for medication delivery provides an efficient and relatively painless mode of analgesia delivery. As well, ketamine is well-known to be an effective analgesic and to preserve cardiorespiratory function thus removing the necessity of physiologic monitoring that is obligatory when using opioids. The use of ketamine by the IN route provides a rapid, easy-administered and well-tolerated method for providing analgesia in the ED setting.

Details

Lead sponsor	Lions Gate Hospital
Phase	Phase 4
Status	COMPLETED
Enrolment	40
Start date	2012-10
Completion	2013-01

Conditions

• Pain

Interventions

• Intra-nasal ketamine

Primary outcomes

• Proportion of subjects achieving a 13mm or more reduction in pain as measured on a 100-mm VAS within 30 minutes. — 30 minutes

Countries

Canada