Antagonism Research Between Antiemetics Agents (Droperidol, Dexametasone, Ondansetron) and Acetaminophen in Thyroidectomy's Post-operative Analgesia. (ANPATHY)

NCT01679093 Phase 3 COMPLETED

The purpose of our study is to determine if there is an antagonism between drugs used in the prevention of postoperative nausea and vomiting (PONV) on the analgesia led by acetaminophen after thyroidectomy.

Details

Lead sponsor	University Hospital, Lille
Phase	Phase 3
Status	COMPLETED
Enrolment	66
Start date	2009-06
Completion	2011-06

Conditions

• Interaction Between Antiemetic Drugs and Paracetamol

Interventions

• ondansetron
• Droperidol
• Dexamethasone

Primary outcomes

• "electric nociception threshold" measured by PainMatcher — during 2 hours after thyroidectomy in the postoperative care unit
  The PainMatcher is a pain self-assessment device using the electric stimulation of the median nerve. The patient maintains a pressure on an electrode box between the thumb and the index finger, creating a current of increasing intensity. The threshold of pain sensation is obtained when the patient releases his fingers from the electrode box. So whe raise the electric nociceptive threshold showned by the PainMatcher. We realize two measures and consider the second one. objective measure.

Countries

France