Probiotics and Allergic Diseases (probiotics)

NCT01635738 NA COMPLETED

Many studies had demonstrated that probiotics could be applied in the prevention and adjuvant treatment for allergic diseases. In this study, we investigate the effects of Lactobacillus paracasei GMNL-133(LP), Lactobacillus fermentum GM-090 (LF), and Lactobacillus paracasei GMNL-133(LP) with Lactobacillus fermentum GM-090 (LF) combination products used for adjuvant treatment of atopic dermatitis and asthma.

Details

Lead sponsor	GenMont Biotech Incorporation
Phase	NA
Status	COMPLETED
Enrolment	240
Start date	2011-12
Completion	2014-06

Conditions

• Atopic Dermatitis
• Asthma

Interventions

• LP GMNL-133 capsule
• LF GM-090 capsule
• LP GMNL-133 +LF GM-090 capsule
• Placebo

Primary outcomes

• The Effects of probiotics in improving life quality and symptomatic severity — 2 years
  1. Atopic dermatitis Primary Endpoints: SCORAD score, Children's Dermatology Life Quality Index (CDLQI), and Dermatitis Family Impact Questionnaire 2. Asthma Primary Endpoints: GINA guideline asthma severity ( step up or step down) ACT, PAQLQ, PACQLQ, PASS Questionnaire 3. Allergic Rhinitis Primary Endpoints: ARIA allergic rhinitis severity PRQLQ, NTSS Questionnaire

Countries

Taiwan