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Onset and Duration of Action of Mometasone Inhalation Powder as Measured by Oscillometry Versus Spirometry
Inhaled corticosteroids (ICS) are appreciated for their long term anti-inflammatory effects in chronic asthma. However, they also have largely unappreciated early effects when initiated as a controller therapy in a steroid-naïve population. Impulse oscillometry might reveal such an early effect better than spirometry. The investigators sought to examine the onset of action and sustained effects over 4 weeks treatment of mometasone furoate as measured by Impulse Oscillometry System (IOS) versus spirometry.
Details
| Lead sponsor | California Allergy and Asthma Medical Group, Inc. |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 21 |
| Start date | 2011-06 |
Conditions
- Asthma
Interventions
- Mometasone furoate 220
- KoKo Spirometry
- Mometasone furoate 440
- Oscillometry
Primary outcomes
- IOS — 4 weeks
Measurement of pulmonary function.
Countries
United States