Prospective Randomized Controlled Multicenter Trial of 4 Antiseptic Strategies for Prevention of Catheter Infection in Intensive Care Unit for Adults Patients (CLEAN)

NCT01629550 Phase 4 COMPLETED

Catheter related infection is the third cause of nosocomial infection in ICUs. Most of them are avoidable and can be prevent by improving aseptic practices during catheter insertion and maintenance. Indeed, the main route of catheter contamination for short-term catheters is the insertion site. Consequently, the quality of skin disinfection is the most effective preventive measure to reduce the incidence of these infections. This aim of the present study is to compare four strategies of skin disinfection to determine whether a 2% alcoholic solution of chlorhexidine acts better than 5% alcoholic povidone iodine in reducing catheter infection and to assess whether a detersion phase prior to disinfection reduces catheter colonization as compared with no detersion.

Details

Lead sponsor	Poitiers University Hospital
Phase	Phase 4
Status	COMPLETED
Enrolment	2400
Start date	2012-10

Conditions

• Preventing Catheter Related Infection

Interventions

• skin disinfection prior catheter insertion

Primary outcomes

• Major catheter related infection

Countries

France