A Randomized, Double-blind Comparison of Single Dose Prochlorperazine Versus Acetaminophen, Aspirin and Caffeine for the Treatment of Acute Migraine in the Emergency Department.

NCT01629329 Phase 4 TERMINATED Results posted

The objective of this randomized, double blind study is to demonstrate that one dose oral "excedrin migraine" (acetaminophen, aspirin and caffeine) is not inferior when compared to one dose of intravenous prochlorperazine for the treatment of acute migraine headaches in the emergency department.

Details

Lead sponsor	Albert Einstein Healthcare Network
Phase	Phase 4
Status	TERMINATED
Enrolment	93
Start date	2010-11
Completion	2014-07

Conditions

• Migraine Headaches

Interventions

• Aspirin, Acetaminophen, Caffeine pills
• Prochlorperazine 10mg

Primary outcomes

• Mean Difference From Baseline of VAS Pain Scores — 60 minutes from drug administration
  0 Participants analyzed. PI has left the institution. Efforts made to contact were unsuccessful. No data available

Countries

United States