Prevention of Arrhythmia Device Infection Trial (PADIT) Cluster Crossover Study

NCT01628666 Phase 4 COMPLETED

The goal of the study is to compare whether a center-wide policy of incremental antibiotic therapy will reduce CIED infection rate compared to a policy of conventional antibiotic prophylaxis in high-risk patients undergoing arrhythmia device procedures. All antibiotics used are approved for use and readily available.

Details

Lead sponsor	Population Health Research Institute
Phase	Phase 4
Status	COMPLETED
Enrolment	12814
Start date	2012-12
Completion	2017-09-08

Conditions

• Arrhythmia

Interventions

• Incremental
• Conventional

Primary outcomes

• Hospitalization attributed to device infection — Evaluation is one year post patient's procedure

Countries

Canada