NCT01619917

The Role of Fractional Vascular Laser Therapy in the Management of Burn Scars

Recruiting now NA Last updated 4 December 2024

What this trial tests

NA trial testing Fractional Vascular Laser in Burn Scar in 6 participants. Currently enrolling.

Timeline

1 November 2012

Primary endpoint
1 June 2027

1 July 2028

Quick facts

Lead sponsor	University of Manitoba
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	single group
Masking	single
Primary purpose	treatment
Enrollment	6
Start date	1 November 2012
Primary completion	1 June 2027
Estimated completion	1 July 2028
Sites	1 location across Canada

Drugs / interventions tested

• Fractional Vascular Laser

Conditions studied

• Burn Scar — all drugs for Burn Scar →

Sponsor

University of Manitoba

Who can join

Adults 18 to 60, any sex, with Burn Scar. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

While the literature tends to support the use of laser therapy in the management of burn scars, there is a definite lack of appropriately powered, randomized controlled trials. Laser therapy can be quite expensive when compared to other treatment modalities for burn scars, and while promising, its true usefulness has yet to be conclusively demonstrated. For this reason, our assessing the effects of fractional vascular lasers on burn scars. It has been hypothesized that the fractional vascular lasers work on mature scars to decrease scar formation, and the fractional laser works on scar that is quiescent to promote remodelling. The retexturing/ resurfacing of the laser theoretically can decrease the visibility of the mesh pattern created by meshed split thickness skin graft).

Objective:

To determine the benefit of fractional vascular laser treatment in improving burn scar height, texture, vascularity and pliability in late burn scars.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Advancements in Regenerative Strategies Through the Continuum of Burn Care.
   Stone Ii R, Natesan S, Kowalczewski CJ, Mangum LH, et al · · 2018 · cited 73× · PMID 30038569 · DOI 10.3389/fphar.2018.00672