National Institutes of Health Clinical Center (CC)
Who can join
18 and older, any sex, with Rheumatoid Arthritis or Arthritis. Patients with the condition only — healthy volunteers not accepted.
Results — posted to ClinicalTrials.gov
Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.
Self-Efficacy ExercisePrimary· Baseline
The Chronic Disease Self-Efficacy-Exercise Regularly Scale is a 3-item scale used to measure confidence in exercising regularly based on a Likert scale from 1 (not at all confident) to 10 (totally confident). The mean value was calculated based on participant responses to all three items.
Group
Value
95% CI
Yoga
6.1
4.0 – 8.1
Self-Efficacy ExercisePrimary· 8 weeks
The Chronic Disease Self-Efficacy-Exercise Regularly Scale is a 3-item scale used to measure confidence in exercising regularly based on a Likert scale from 1 (not at all confident) to 10 (totally confident). The mean value was calculated based on participant responses to all three items.
Group
Value
95% CI
Yoga
7.5
6.8 – 8.1
Health-Promoting Lifestyle Profile II ScorePrimary· Baseline
Health Promoting Lifestyle Profile (HPLP II) was used to measure the extent to which adults engage in a health-promoting lifestyle - Likert-type scales ranged from (1-never to 4-routinely). Subscales included: spiritual growth, interpersonal relations, nutrition, physical activity, health responsibility, and stress management. The mean value was calculated based on participant responses to all six subscales.
Group
Value
95% CI
Yoga
2.3
2.0 – 2.6
Health-Promoting Lifestyle Profile II ScorePrimary· 8 weeks
Health Promoting Lifestyle Profile (HPLP II) was used to measure the extent to which adults engage in a health-promoting lifestyle - Likert-type scales ranged from (1-never to 4-routinely). Subscales included: spiritual growth, interpersonal relations, nutrition, physical activity, health responsibility, and stress management. The mean value was calculated based on participant responses to all six subscales.
Group
Value
95% CI
Yoga
2.8
2.5 – 3.1
Adverse events — posted to ClinicalTrials.gov
Time frame: 8 weeks.
Reporting threshold: 0%.
Adverse-event reports describe events observed during the trial — not all are caused by the drug.
Background:
* People with arthritis should be active. Regular exercise leads to less pain, more energy, improved sleep, and better day-to-day function. Yet arthritis is one of the most common reasons people give for limiting activities.
* Yoga for arthritis has been studied before. However, few studies have included minorities. Making changes to yoga classes based on language and culture may help people use yoga to care for their arthritis symptoms. Researchers want to see if minority populations with arthritis will come to and benefit from yoga classes.
Objectives:
\- To see if yoga classes designed for people with arthritis will be acceptable to minorities with arthritis.
Eligibility:
* Adults at least 18 years of age who are enrolled in the Natural History of Rheumatic Disease in Minority Communities study.
* Participants will have osteoarthritis or rheumatoid arthritis.
* Participants will be able to speak and read English or Spanish.
Design:
* The total study period covers 10 weeks.
* The first study visit will include an initial questionnaire about health and arthritis. Participants will also have a physical exam.
* Participants will have yoga classes twice a week for 8 weeks. The classes will be 1 hour long each.
* After completing the yoga classes, participants will complete another questionnaire about their health. They will have a final physical exam.
* Follow-up contact will be made 3 months after the end of the study.
Publications & conference data
6 peer-reviewed publications reference this trial (live from Europe PMC):
NCT06559852 — The Impact of Yoga on Endometriosis-Related Pain
· NA
· recruiting
NCT07485790 — The Effects of Yoga on Pregnant Women
· NA
· recruiting
NCT07480174 — Effects of Tai Chi and Yoga on Flexibility, Anxiety, and Sleep Quality in Women
· NA
· recruiting
NCT06949007 — Yoga for Persistent Post-Surgical Pain (PPSP)
· NA
· recruiting
NCT07415850 — The Effect of a Four-Week Hatha Yoga Intervention to Improve Quality of Life, Anxiety, and Depressive Symptoms in Indivi
· NA
· not yet recruiting
Other recruiting trials for Rheumatoid Arthritis
Currently open trials in the same condition.
NCT07433335 — A Study to Assess the Safety and Tolerability of SR-878 in Patients With Rheumatoid Arthritis
· Phase 1
· recruiting
NCT07491016 — Efficacy and Safety of Telitacicept Combined With Baricitinib for Refractory Rheumatoid Arthritis
· recruiting
NCT07171983 — A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-986454 in Participants With Rheumatoid Arthritis
· Phase 1
· recruiting
NCT07246096 — Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Rel
· EARLY_PHASE1
· recruiting
NCT07363590 — A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004)
· Phase 1
· recruiting
Other National Institutes of Health Clinical Center (CC) trials
Trials by the same sponsor.
NCT06998134 — Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults
· recruiting
NCT05473429 — Characterization of Nociception Phenotype in Individuals With Intellectual Disability
· NA
· recruiting
NCT07295795 — Blood Sampling Pre- and Post-Propofol Administration to Characterize the Blood Proteome Using Different Research Assays
· recruiting
NCT05663320 — A Study of a Virtual Education-Based Transition Intervention to Improve Transition Readiness in Adolescent and Young Adu
· NA
· withdrawn
NCT06778252 — UrbanHEAT: Health Behaviors, Outcomes, and Disparities in Individually Experienced Temperature Across an Urban Community
· withdrawn
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Institutes of Health Clinical Center (CC)
Last refreshed: 16 July 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01617421.