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NCT01600612
Oxytocin, Carbetocin and Misopristol for Treatment of Postpartum Hemorrhage: A Multicentric Randomized Trial
NA trial testing carbetocin in Postpartum Hemorrhage in 300 participants. Status unknown.
1 June 2013
Quick facts
| Lead sponsor | Sohag University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 300 |
| Start date | 1 September 2012 |
| Primary completion | 1 June 2013 |
| Estimated completion | 1 July 2013 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- carbetocin (CARBETOCIN) — full drug profile →
- misopristol — full drug profile →
- oxytocin (OXYTOCIN) — full drug profile →
Conditions studied
- Postpartum Hemorrhage — all drugs for Postpartum Hemorrhage →
Sponsor
Sohag University
Who can join
Eligibility, female only, with Postpartum Hemorrhage. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
control of postpartum hemorrhage
Time frame: within 20 minutes of administration
Sponsor's own description
Postpartum hemorrhage (PPH) is the leading cause of maternal death worldwide, with an estimated mortality of 140 000 per year. Uterine atony is one of the most important causes of PPH. The traditional treatment of which is the use of uterotonic agents. Oxytocin is the most conventional drug which was proved effective. However, it has the shortcomings of short half life and the necessity of intravenous administration. Misopristol, and more recently Carbetocin were introduced for treatment of atonic PPP not responding to Oxytocin. Aim of the study is to evaluate the effectiveness of Carbetocin, Misopristol, and Oxytocin for treatment of atonic PPH.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Uterotonic agents for first-line treatment of postpartum haemorrhage: a network meta-analysis.
Parry Smith WR, Papadopoulou A, Thomas E, Tobias A, et al · · 2020 · cited 25× · PMID 33232518 · DOI 10.1002/14651858.cd012754.pub2
Verify or expand the search:
- PubMed search for NCT01600612
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of carbetocin
Trials testing the same drug.
- NCT03710317 — Carbetocin Versus Buccal Misoprostol Plus IV Tranexamic Acid for Prevention of Postpartum Hemorrhage at Cesarean Section · NA · completed
- NCT03708497 — Carbetocin Versus Oral Tranexamic Acid Plus, Buccal Misoprostol on Blood Loss After Vaginal Delivery · NA · completed
- NCT03693599 — Carbetocin Versus Syntometrine in Obese Women Undergoing Elective Cesarean · Phase 4 · completed
Other recruiting trials for Postpartum Hemorrhage
Currently open trials in the same condition.
- NCT07401160 — Umbilical Cord Drainage to Prevent Postpartum Hemorrhage · NA · recruiting
- NCT07278037 — Trends in the Administration of Tranexamic Acid for Postpartum Hemorrhage · recruiting
- NCT07279545 — The Effect of Placental Cord Drainage on the Third Stage of Labor and the Amount of Postpartum Bleeding · NA · recruiting
- NCT07229573 — The Effectiveness of Serious Game-Based Training for Nursing Students in Postpartum Haemorrhage Management · NA · recruiting
- NCT07005349 — THUMB: Multi-centre Cluster Trial for Caesarean Section Haemorrhage · NA · recruiting
Other Sohag University trials
Trials by the same sponsor.
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- NCT07519694 — Comparative Study Between Different Additives to Lidocaine 2٪ for Peribulbar Block in Vitreoretinal Surgery · NA · not yet recruiting
- NCT07515365 — Colitis Patterns in Patients With Lower GI Symptoms · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01600612 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sohag University
- Last refreshed: 30 May 2013
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01600612.
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