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NCT01597726
Cervical Priming Before Dilation & Evacuation: a Randomized Controlled Trial
NA trial testing Misoprostol in Abortion, Induced in 159 participants. Completed in 1 June 2013.
1 June 2013
Quick facts
| Lead sponsor | Ibis Reproductive Health |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 159 |
| Start date | 1 May 2012 |
| Primary completion | 1 June 2013 |
| Estimated completion | 1 June 2013 |
| Sites | 1 location across South Africa |
Drugs / interventions tested
- Misoprostol (Misoprostol) — full drug profile →
- Laminaria
Conditions studied
- Abortion, Induced — all drugs for Abortion, Induced →
Sponsor
Ibis Reproductive Health — full company profile →
Who can join
18 and older, female only, with Abortion, Induced. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Proportion of women with fetal expulsion prior to dilation and evacuation
Time frame: Prior to D&E procedure
Sponsor's own description
The purpose of this study is to compare the efficacy of buccal misoprostol cervical priming to laminaria priming among women undergoing D\&E at 13-20 weeks gestation in the Western Cape Province, South Africa
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
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The costs and cost effectiveness of providing second-trimester medical and surgical safe abortion services in Western Cape Province, South Africa.
Lince-Deroche N, Constant D, Harries J, Kluge J, et al · · 2018 · cited 12× · PMID 29953434 · DOI 10.1371/journal.pone.0197485
Verify or expand the search:
- PubMed search for NCT01597726
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Misoprostol
Trials testing the same drug.
- NCT07353281 — Carbetocin vs Misoprostol for Postpartum Hemorrhage Prevention · NA · not yet recruiting
- NCT06669533 — Use Misoprostol to Optimize Prevention of Cervical Cancer · NA · recruiting
- NCT07416487 — Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor · NA · completed
- NCT06765473 — Comparison Between Preoperative Vaginal and Postoperative Sublingual Misoprostol for Prevention of Postpartum Hemorrhage · Phase 3 · not yet recruiting
- NCT06452719 — Letrozole and Misoprostol for Early Pregnancy Loss Management · Phase 2 · recruiting
Other Ibis Reproductive Health trials
Trials by the same sponsor.
- NCT04181021 — Evaluation of Values Clarification and Attitude Transformation Workshops on Abortion and Family Planning Service Provisi · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01597726 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ibis Reproductive Health
- Last refreshed: 6 November 2013
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01597726.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing