Who is sponsoring NCT01589081?

NCT01589081 is sponsored by Mclean Hospital.

What condition does NCT01589081 study?

NCT01589081 studies Nicotine Dependence.

What drugs are being tested in NCT01589081?

Interventions: Intravenous Nicotine, Progesterone.

What is the status of NCT01589081?

NCT01589081 is currently WITHDRAWN.

Last reviewed 2024-01-15 · How we verify

Effects of Progesterone on IV Nicotine-Induced Changes in Hormones and Subjective Ratings of Stimulant Drug Effect

NCT01589081 NA WITHDRAWN

The proposed clinical studies will analyze the interactions between progesterone, nicotine, alterations in endocrine hormones, mood and cardiovascular measures. It is hypothesized that the administration of progesterone at a dose that mimics luteal phase levels in normal cycling women will diminish the positive subjective effects of nicotine, as has been consistently observed for cocaine. This novel approach could have direct implications for facilitating smoking cessation treatment in women of reproductive age

Details

Lead sponsor	Mclean Hospital
Phase	NA
Status	WITHDRAWN
Start date	2008-09
Completion	2015-12-01

Conditions

Nicotine Dependence

Interventions

Intravenous Nicotine
Progesterone

Primary outcomes

Effects of Progesterone on IV nicotine hormones and mood — From baseline to study completion (approximately 1 year)
We are examining the effects of progesterone on IV nicotine induced changes in serum/plasma hormone levels and subjective states, as measured by a visual analog scale.

Countries

United States