Who is sponsoring MARCH VE?

MARCH VE is sponsored by Kirby Institute.

What condition does MARCH VE study?

MARCH VE studies Cardiovascular Disease.

What drugs are being tested in MARCH VE?

Interventions: NRTI + PI, maraviroc + PI, maraviroc + NRTI.

What is the status of MARCH VE?

MARCH VE is currently COMPLETED.

Last reviewed 2016-01-18 · How we verify

Maraviroc Switch Vascular Endothelium (VE) Substudy: a Substudy of MARCH (MARCH VE)

NCT01585753 COMPLETED

This is a substudy of MARCH, in which we are exploring the changes in the vascular endothelium using pulse wave tonometry (a non invasive measure of cardiac health) to measure the changes in small and large arterial elasticity in participants of the MARCH study who switch to maraviroc-based regimens over 96 weeks of follow-up.

Details

Lead sponsor	Kirby Institute
Status	COMPLETED
Enrolment	34
Start date	2012-06
Completion	2015-12

Conditions

Cardiovascular Disease

Interventions

NRTI + PI
maraviroc + PI
maraviroc + NRTI

Primary outcomes

Mean change in small arterial elasticity (SAE) as measure by pulse wave tonometry — 96 weeks
measured at 6 timepoints week 0, 4, 12, 24, 48, 96

Countries

Argentina, Australia, Germany, Thailand