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Autologous Blood Transfusion After Local Infiltration Analgesia With Ropivacaine in Total Knee and Hip Arthroplasty
Total knee and hip arthroplasty for osteoarthritis is performed on still broader indications even in elderly patients with previous or current medical conditions. Especially comorbidity like cardiovascular diseases and conditions with increased risk of bleeding or previous thrombo-embolic events are major challenges. To facilitate safe use of ropivacaine as an analgesic, information on the concentrations levels after autologous blood transfusion following local infiltration analgesia is very crucial. However, very limited data are available. To verify the safety of autologous blood transfusion, ropivacaine concentrations were studied in 52 patients undergoing either total knee arthroplasty or total hip arthroplasty.
Details
| Lead sponsor | Northern Orthopaedic Division, Denmark |
|---|---|
| Status | COMPLETED |
| Enrolment | 52 |
| Start date | 2010-03 |
| Completion | 2010-06 |
Conditions
- Total Hip Arthroplasty
- Total Knee Arthroplasty
Interventions
- Autologous blood transfusion with ropivacaine
- Autologous blood transfusion with ropivacaine
Primary outcomes
- Concentrations of ropivacaine in serum — 6 hours
Concentrations of ropivacaine in serum before and after autologous blood transfusion will be analyzed.
Countries
Denmark