Increased Second-line Eradication Rate of Helicobacter Pylori by Adding N-acetylcystein or Metronidazole to the Conventional Triple Therapy.

NCT01572597 Phase 4 UNKNOWN

Compare efficacy and safety of 10-day triple therapy (rabeprazole, clarithromycin and amoxicillin) plus N-acetylcystein versus 10-day concomitant therapy (rabeprazole, clarithromycin, amoxicillin and metronidazole) for re-eradication for gastric Helicobacter pylori infection.

Details

Lead sponsor	Buddhist Tzu Chi General Hospital
Phase	Phase 4
Status	UNKNOWN
Enrolment	120
Start date	2011-06
Completion	2012-12

Conditions

• Bacterial Infection Due to Helicobacter Pylori (H. Pylori)

Interventions

• 10RAC+acetylcystein
• 10RAC+metronidazole

Primary outcomes

• Re-eradication rate — 4 weeks after complete use of drug for treatment
  A negative post-treatment 13C-urea breath test result at more than 4 weeks after complete use of drug for treatment.

Countries

Taiwan