NCT01570010: CRC-NORDIET

The Norwegian Dietary Guidelines and Colorectal Cancer Survival Study

Active, enrolled NA Last updated 27 February 2026

What this trial tests

NA trial testing Norwegian food based dietary guidelines in Colorectal Cancer in 503 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

1 March 2012

Primary endpoint
31 December 2034

31 December 2040

Quick facts

Lead sponsor	University of Oslo
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	basic science
Enrollment	503
Start date	1 March 2012
Primary completion	31 December 2034
Estimated completion	31 December 2040
Sites	3 locations across Norway

Drugs / interventions tested

• Norwegian food based dietary guidelines

Conditions studied

• Colorectal Cancer — all drugs for Colorectal Cancer →

Sponsor

University of Oslo

Who can join

Adults 50 to 80, any sex, with Colorectal Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The current study is designed to gain a better understanding of the role of a healthy diet aimed at dampening inflammation and oxidative stress on long-term disease outcomes and survival in colorectal cancer patients. Since previous research on the role of diet for colorectal cancer survivors is limited, the study may be of great importance for this cancer population.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

1. The Norwegian dietary guidelines and colorectal cancer survival (CRC-NORDIET) study: a food-based multicentre randomized controlled trial.
   Henriksen HB, Ræder H, Bøhn SK, Paur I, et al · · 2017 · cited 27× · PMID 28137255 · DOI 10.1186/s12885-017-3072-4
2. Relative validity of a short food frequency questionnaire assessing adherence to the Norwegian dietary guidelines among colorectal cancer patients.
   Henriksen HB, Carlsen MH, Paur I, Berntsen S, et al · · 2018 · cited 23× · PMID 29545734 · DOI 10.29219/fnr.v62.1306
3. Validation of two short questionnaires assessing physical activity in colorectal cancer patients.
   Henriksen HB, Berntsen S, Paur I, Zucknick M, et al · · 2018 · cited 12× · PMID 29854408 · DOI 10.1186/s13102-018-0096-2
4. Associations of the 2018 World Cancer Research Fund/American Institute of Cancer Research (WCRF/AICR) cancer prevention recommendations with stages of colorectal carcinogenesis.
   Kvaerner AS, Andersen AR, Henriksen HB, Knudsen MD, et al · · 2023 · cited 5× · PMID 37212529 · DOI 10.1002/cam4.6119
5. How many days of continuous physical activity monitoring reliably represent time in different intensities in cancer survivors.
   Western B, Demmelmaier I, Vistad I, Hansen BH, et al · · 2023 · cited 4× · PMID 37093874 · DOI 10.1371/journal.pone.0284881
6. Plant-based diet and oxidative stress-induced DNA damage in post-surgery colorectal cancer patients: Results from a randomized controlled trial.
   Nordengen AL, Krutto A, Kværner AS, Alavi DT, et al · · 2025 · cited 2× · PMID 40180023 · DOI 10.1016/j.freeradbiomed.2025.03.047
7. Predictive equations commonly used in the clinic underestimate resting energy expenditure compared with whole-room indirect calorimetry in colorectal cancer survivors.
   Eklo RR, Alavi DT, Konglevoll DM, Kolle Å, et al · · 2026 · PMID 41611086 · DOI 10.1016/j.ajcnut.2026.101209
8. Spillover effect of a dietary intervention on physical activity in a randomized controlled trial with colorectal cancer patients.
   Henriksen HB, Kolle Å, Stenling A, Paur I, et al · · 2025 · PMID 40346639 · DOI 10.1186/s12966-025-01757-0