Assessment of Sensory and Motor Block After Intrathecal Administration of Bupivacaine, Ropivacaine and Levo-bupivacaine Combined With Small Doses of Fentanyl, Followed by Administration of Normal Saline Epidurally:a Clinical Trial in Parturients Scheduled for C-section

NCT01558713 Phase 2/Phase 3 UNKNOWN

Intrathecal (i.t.) administration of isobaric bupivacaine, ropivacaine and levobupivacaine with addition of fentanyl for c-section either combined or not with administration of 10 ml of N/S 0,9% epidurally, in order to extent epidural space.Sensory and motor block profile, haemodynamics and side effects were assessed.

Details

Lead sponsor	University of Patras
Phase	Phase 2/Phase 3
Status	UNKNOWN
Enrolment	120
Start date	2010-01
Completion	2012-12

Conditions

• Stillborn Caesarean Section

Interventions

• Bupivacaine- Fentanyl - Normal Saline
• Ropivacaine-Fentanyl-Normal Saline
• Levobupivacaine- Fentanyl- Normal Saline
• Bupivacaine + Fentanyl
• Ropivacaine + Fentanyl
• Levobupivacaine + Fentanyl

Primary outcomes

• Dermatomes of Sensory block — up to 120 minutes average
  Dermatomes of sensory block(pin prick test) are assessed every minute for the first 30 minutes after the intrathecal administration of local anesthetics and there after every 5 minutes until withdrawal of sensory block
• Motor block — up to 120 minutes average
  Motor block according to the Bromage scale are assessed every minute for the first 30 minutes after the intrathecal administration of local anesthetics and there after every 5 minutes until withdrawal motor block

Countries

Greece