NCT01550133

Effects of Food Form on Cephalic Phase Responses

Completed NA Last updated 12 December 2023

What this trial tests

NA trial testing Learned: Non-nutritive beverage to Non-nutritive beverage in Obese in 60 participants. Completed in 30 December 2016.

Timeline

1 September 2012

Primary endpoint
30 April 2016

30 December 2016

Quick facts

Lead sponsor	Purdue University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	basic science
Enrollment	60
Start date	1 September 2012
Primary completion	30 April 2016
Estimated completion	30 December 2016
Sites	1 location across United States

Drugs / interventions tested

• Learned: Non-nutritive beverage to Non-nutritive beverage
• Learned: Nutritive solid to Nutritive solid
• Learned: Nutritive beverage to Nutritive beverage
• Not Learned: Non-nutritive solid to Nutritive solid
• Not Learned: Nutritive beverage to Non-nutritive beverage
• Not Learned: Non-Nutritive solid to Non-nutritive solid
• Not Learned: Non-nutritive beverage to Nutritive beverage
• Not Learned: Non-Nutritive solid to Non-Nutritive Solid

Conditions studied

• Obese — all drugs for Obese →
• Overweight — all drugs for Overweight →

Sponsor

Purdue University

Who can join

Adults 18 to 50, any sex, with Obese or Overweight. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study has two main aims: 1) To determine if ingestion of solid or beverage food forms will change appetite hormone responses, and 2) To determine whether "learning" (defined as 2 week daily consumption) about the metabolic consequence of ingesting solid or beverage foods forms varying in energy alters appetite hormone responses.

Beverage consumption has been implicated in the problem of obesity. However, the exact relationship between beverages, lower appetitive response and lower compensatory dietary responses remains unclear. This study aims to address this gap in the research. For aim 1, the null hypothesis is that the energy in beverage and solid forms will not affect appetite hormonal responses differently. The alternative hypothesis is that exposure to the energy-yielding beverage will elicit a lower appetitive hormone response compared to oral exposure to the solid food form. For aim 2, the null hypothesis is that learning will not change appetite hormone responses. The alternative hypothesis is that learning will decrease appetite hormone responses in the non-energy-yielding beverage more than in the energy-yielding beverage.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.