The Effect of Various Types of the Renin-angiotensin-aldosterone System Blockade on Proteinuria in Chronic Non-diabetic Kidney Disease: a Double-blind Cross-over Randomised Controlled Study

NCT01541267 Phase 4 COMPLETED

The main purpose of the study is to compare the effects of three different types of RAAS blockade on 24 hours proteinuria in patients with non-diabetic chronic kidney disease.

Details

Lead sponsor	Medical University of Gdansk
Phase	Phase 4
Status	COMPLETED
Enrolment	20
Start date	2009-12
Completion	2011-11

Conditions

• Chronic Kidney Disease
• Proteinuria

Interventions

• aliskiren, eplerenon, telmisartan

Primary outcomes

• Difference in urinary albumin-to-creatinine ratio (UACR) between treatment arms — baseline and the end of 8 week treatments
  changes of UACR