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Evaluation of Early Wound Healing Following Use of Fibrin Sealant (FS) in Periodontal Surgery. A Controlled Randomized Clinical Trial.
The aim of this randomized controlled clinical trial is to compare wound healing after the use of fibrin sealant and sutures for gum surgeries. 15 patients requiring gum surgery for their periodontal (gum)problems are selected and invited. Two regions will be operated in a selected patient. One region will receive fibrin sealant (test site) and the other region will get sutures (control site). Wound healing will be assessed by evaluating inflammatory markers, Interleukin 1beta and interleukin 8, from a non invasively collected gum fluid. Hypothesis. Fibrin sealant use will result in less inflammation seen through reduced levels of interleukin (1beta and 8) compared to use of sutures.
Details
| Lead sponsor | Chhattisgarh Dental College and Research Institute |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 15 |
| Start date | 2012-04 |
| Completion | 2012-12 |
Conditions
- Periodontitis
Interventions
- Fibrin Sealant
- Suture
Primary outcomes
- Concentration of cytokines. — 7 days
Assess the concentration of Interleukin 1beta and Interleukin 8 in GCF of test and control sites after 7 days.
Countries
India