Who is sponsoring NCT01534676?

NCT01534676 is sponsored by Columbia University.

What condition does NCT01534676 study?

NCT01534676 studies Sickle Cell Disease, Thalassemia.

What drugs are being tested in NCT01534676?

Interventions: Transfusion, Blood, Chelation therapy.

What is the status of NCT01534676?

NCT01534676 is currently TERMINATED.

Last reviewed 2016-08-11 · How we verify

Harmful Effects of Transfusion of Older Stored Red Cells: Iron and Inflammation

NCT01534676 NA TERMINATED Results posted

The purpose of this study is to determine the effects of transfusion of fresh and stored blood on patients. The investigators hope to test: * whether a similar effect (older stored blood is associated with worse outcomes) is seen in chronically transfused patients with hemoglobinopathies. This patient population will also allow the investigators to test whether iron- chelation therapy is beneficial in this setting. * whether washing or cryopreserving the red blood cells has any effect on this outcome. These findings may explain the immunomodulatory effects of older stored blood in patients and will help us develop safer transfusion products for patients.

Details

Lead sponsor	Columbia University
Phase	NA
Status	TERMINATED
Enrolment	3
Start date	2012-02
Completion	2013-03

Conditions

Sickle Cell Disease
Thalassemia

Interventions

Transfusion
Blood
Chelation therapy

Primary outcomes

Non-transferrin-bound Iron Level — 2 hours after transfusion

Countries

United States