NCT01514110 is a Phase 1, PHASE2 clinical trial of RAD001 in Gastric Cancer, sponsored by Chinese University of Hong Kong.

Who is sponsoring NCT01514110?

NCT01514110 is sponsored by Chinese University of Hong Kong.

What drugs are being tested in NCT01514110?

Interventions in NCT01514110: RAD001.

What condition does NCT01514110 study?

NCT01514110 studies Gastric Cancer.

Is NCT01514110 still recruiting?

NCT01514110 is currently completed. Last updated 2 April 2019.

Last reviewed 2019-04-02 · How we verify

NCT01514110

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Gastric Cancer RAD001 Study

Completed Phase 1, PHASE2 Last updated 2 April 2019

What this trial tests

Phase 1, PHASE2 trial testing RAD001 in Gastric Cancer in 35 participants. Completed in 6 March 2019.

Timeline

23 January 2008

Primary endpoint
6 March 2019

6 March 2019

Quick facts

Lead sponsor	Chinese University of Hong Kong
Phase	Phase 1, PHASE2
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	35
Start date	23 January 2008
Primary completion	6 March 2019
Estimated completion	6 March 2019
Sites	1 location across Hong Kong

Drugs / interventions tested

RAD001 — full drug profile →

Conditions studied

Gastric Cancer — all drugs for Gastric Cancer →

Sponsor

Chinese University of Hong Kong

Who can join

18 and older, any sex, with Gastric Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to determine dose limiting toxicities (DLT) and maximum tolerated dose (MTD) of RAD001, as well as to assess tumor response and overall survival.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

The mTOR pathway in obesity driven gastrointestinal cancers: Potential targets and clinical trials.
Malley CO, Pidgeon GP. · · 2016 · cited 29× · PMID 27051587 · DOI 10.1016/j.bbacli.2015.11.003
Adipose tissue dysfunction and its effects on tumor metabolism.
Diedrich J, Gusky HC, Podgorski I. · · 2015 · cited 27× · PMID 25781550 · DOI 10.1515/hmbci-2014-0045

Verify or expand the search:

Other trials of RAD001

Trials testing the same drug.

NCT04895748 — DFF332 as a Single Agent and in Combination With Everolimus & Immuno-Oncology Agents in Advanced/Relapsed Renal Cancer & · Phase 1 · terminated
NCT02991807 — RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome · Phase 1, PHASE2 · completed
NCT01713946 — A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With · Phase 3 · completed
NCT01743560 — An Open Label Study of Postmenopausal Women With Oestrogen Receptor Positive Locally Advanced or Metastatic Breast Cance · Phase 4 · completed
NCT01544491 — Efficacy, Tolerability and Safety of Early Introduction of Everolimus, Reduced Calcineurin Inhibitors and Early Steroid · Phase 3 · completed

Other recruiting trials for Gastric Cancer

Currently open trials in the same condition.

NCT07525765 — AI-assisted Decision-making of Reoperation for Postoperative Bleeding of Gastric Cancer · recruiting
NCT07464470 — Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Gastroesophageal Cancers · recruiting
NCT07432633 — [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications · Phase 1, PHASE2 · recruiting
NCT07431281 — Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Meta · Phase 3 · recruiting
NCT07448493 — Local Treatment Strategies for Brain Metastases of Gastric and Esophageal Cancer · active not recruiting

Other Chinese University of Hong Kong trials

Trials by the same sponsor.

NCT07508644 — RSV Vaccination to Reduce Recurrent AECOPD · Phase 4 · not yet recruiting
NCT07230457 — Plasma MTB cfDNA Before Bronchoscopy · not yet recruiting
NCT07288671 — Nostalgia Intervention on Alleviating Loneliness Amongst Older Adults · NA · not yet recruiting
NCT07256457 — Postoperative Pulmonary Function Assessment Based on Deep Learning Study · NA · not yet recruiting
NCT06904209 — Can Artificial Intelligence Reduce Consumption of Standard High Volume Bowel Preparation Regimen Among Older Population, · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01514110 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Chinese University of Hong Kong
Last refreshed: 2 April 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01514110.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing