NCT01502813

Citicoline, Creatine, and Omega-3 Effects in Middle Age Women

Completed NA Results posted Last updated 22 April 2021

What this trial tests

NA trial testing Citicoline, Omega-3 Fatty Acids and Creatine in Cognitive Benefits in 40 participants. Completed in 1 November 2019.

Timeline

1 February 2012

Primary endpoint
30 October 2018

1 November 2019

Quick facts

Lead sponsor	Deborah Yurgelun-Todd
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	40
Start date	1 February 2012
Primary completion	30 October 2018
Estimated completion	1 November 2019
Sites	1 location across United States

Drugs / interventions tested

• Citicoline, Omega-3 Fatty Acids and Creatine — full drug profile →

Conditions studied

• Cognitive Benefits — all drugs for Cognitive Benefits →

Sponsor

Deborah Yurgelun-Todd — full company profile →

Who can join

Adults 40 to 60, female only, with Cognitive Benefits. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Change From Baseline in California Verbal Learning Test (CVLT) That Measure Attention and Memory at 14 Days Primary · Baseline and 14 days from baseline

List B in the California Verbal Learning Test (CVLT) score range 1-16; the score is the number of words recalled so higher scores = better performance/more words recalled.

Group	Value	95% CI
Citicoline, Creatine, and Omega-3 Arm	10	1 – 16

Change From Baseline in WAIS-IV Block Design Subtest A That Measures Attention and Memory at 28 Days Primary · Baseline and 28 days from baseline

WAIS-IV Block Design Subtest A test of visuoconstructional ability is recognized as a test of visuospatial planning and function. It has been shown to be correlated with measures of general intellectual ability. The score range for this measure is 0-129. A score of 90-110 is average for a standard score. The higher the score the better the outcome.

Group	Value	95% CI
Citicoline, Creatine, and Omega-3 Arm	98	0 – 130

Sponsor's own description

The purpose of this study is to determine the functional effects of a citicoline, creatine, and omega-3 fatty acids combination when administered for a duration of four weeks (28 days) to non-psychiatric adult female participants.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.