Neutrophil gElatinase-associated Lipocalin alloWs Intensive treatMent Of cOntrast Induced Nephropathy in Patients With Urgent/Emergency Percutaneous Coronary Intervention (NEW-MOON)

NCT01491243 Phase 4 UNKNOWN

Patients who undergo urgent/emergency coronary angiography can not receive any preventive treatment of contrast induced nephropathy. We tested the hypothesis that Neutrophil gelatinase-associated lipocalin (NGAL), a new biomarker predictive for AKI, allows early and effective treatment of contrast induced nephropathy in patients with urgent/emergency coronary angiography

Details

Lead sponsor	University of Roma La Sapienza
Phase	Phase 4
Status	UNKNOWN
Enrolment	100
Start date	2014-01
Completion	2017-12

Conditions

• Coronary Artery Disease

Interventions

• Intensive treatment with sodium bicarbonate
• Standard treatment with saline infusion

Primary outcomes

• Incidence of contrast induced nephropathy — Baseline and 48 hours after angiography
  Absolute increase in serum creatinine equal to or greater than 0.5 mg/dL detected 48 hours after angiography as compared with baseline value

Countries

Italy