NCT01482819 is a NA clinical trial of galyfilcon A in Myopia, sponsored by Johnson & Johnson Vision Care, Inc..

Who is sponsoring NCT01482819?

NCT01482819 is sponsored by Johnson & Johnson Vision Care, Inc..

What drugs are being tested in NCT01482819?

Interventions in NCT01482819: galyfilcon A, galyfilcon A plus, lotrafilcon A, polymacon, spectacles.

Is NCT01482819 still recruiting?

NCT01482819 is currently completed. Last updated 19 June 2018.

Are results published for NCT01482819?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2018-06-19 · How we verify

NCT01482819

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of Daytime Corneal Swelling During Wear of Galyfilcon A Lenses

Completed NA Results posted Last updated 19 June 2018

What this trial tests

NA trial testing galyfilcon A in Myopia in 21 participants. Completed in 1 December 2011.

Timeline

1 October 2011

Primary endpoint
1 December 2011

1 December 2011

Quick facts

Lead sponsor	Johnson & Johnson Vision Care, Inc.
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	factorial
Masking	single
Primary purpose	treatment
Enrollment	21
Start date	1 October 2011
Primary completion	1 December 2011
Estimated completion	1 December 2011
Sites	1 location across Australia

Drugs / interventions tested

galyfilcon A — full drug profile →
galyfilcon A plus
lotrafilcon A — full drug profile →
polymacon
spectacles

Conditions studied

Myopia — all drugs for Myopia →

Sponsor

Johnson & Johnson Vision Care, Inc. — full company profile →

Who can join

18 and older, any sex, with Myopia. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Corneal Swelling Primary · after 8 hours of lens wear

measured in microns using the Optical Low Coherence Reflectometry (OLCR) Pachymeter. This pachymeter gives corneal thickness measurements to the accuracy of 1 micron (µm)

Group	Value	95% CI
Spectacles	569.42	± 36.0709
Galyfilcon A Plus	574.64	± 39.7804
Galyfilcon A	575.57	± 37.6229
Lotrafilcon A	578.99	± 41.4960
Polymacon	573.79	± 36.1644

Limbal Redness Primary · after 8 hours of lens wear

grade scale of 0 to 4, where 0=None, 1=Trace, 2=Mild, 3=Moderate, 4=Severe; reported as an average grade.

Group	Value	95% CI
Spectacles	0.66	± 0.2479
Galyfilcon A Plus	0.83	± 0.3023
Galyfilcon A	0.77	± 0.3085
Lotrafilcon A	0.91	± 0.3087
Polymacon	1.14	± 0.3363

Endothelia Blebs Primary · after 20 minutes of lens wear

0 to 100% of area; measured as a percentage of corneal area with blebs.

Group	Value	95% CI
Spectacles	4.97	± 3.3703
Galyfilcon A Plus	8.86	± 3.9396
Galyfilcon A	10.93	± 6.6020
Lotrafilcon A	10.31	± 6.6747
Polymacon	8.50	± 3.6000

Sponsor's own description

The purpose of this study is to evaluate corneal swelling, limbal redness, and endothelial bleb response to wearing galyfilcon A lenses in asian eyes.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Polyphenolic Composition of Crataegus monogyna Jacq.: From Chemistry to Medical Applications.
Nabavi SF, Habtemariam S, Ahmed T, Sureda A, et al · · 2015 · cited 48× · PMID 26378574 · DOI 10.3390/nu7095361

Verify or expand the search:

Other recruiting trials for Myopia

Currently open trials in the same condition.

NCT07284966 — Comfort and Vision With TOTAL30 Multifocal Lenses · recruiting
NCT07078799 — Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery · NA · recruiting
NCT07585877 — Effect of Branched-Chain Amino Acid Supplementation on Myopia Progression · NA · active not recruiting
NCT07354945 — An Evaluation of Myopia Control Lenses on Wearing Experience in Myopic Children · NA · recruiting
NCT07229365 — Children's Viewing Behavior · NA · recruiting

Other Johnson & Johnson Vision Care, Inc. trials

Trials by the same sponsor.

NCT07443215 — Evaluation of Effect of Scatter on Visual Performance · NA · recruiting
NCT07174596 — Evaluation of Approved Contact Lenses · NA · completed
NCT07076160 — Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses · NA · completed
NCT06967129 — Evaluation of Daily Disposable Toric Soft Lenses Manufactured With an Alternative Hydration Process · NA · completed
NCT06864858 — Clinical Evaluation of Two Cosmetic Contact Lenses · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01482819 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Johnson & Johnson Vision Care, Inc.
Last refreshed: 19 June 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01482819.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing