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NCT01477736
A Comparison Study of Oxybutynin and Botulinum Toxin for Neurogenic Detrusor Overactivity
NA trial testing Oxybutynin in Spinal Cord Injury in 68 participants. Completed in 1 November 2010.
1 November 2010
Quick facts
| Lead sponsor | Centro de Reabilitação e Readaptação Dr. Henrique Santillo |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 68 |
| Start date | 1 January 2009 |
| Primary completion | 1 November 2010 |
| Estimated completion | 1 November 2010 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Oxybutynin (OXYBUTYNIN) — full drug profile →
- Botulinum toxin A — full drug profile →
Conditions studied
- Spinal Cord Injury — all drugs for Spinal Cord Injury →
Sponsor
Centro de Reabilitação e Readaptação Dr. Henrique Santillo
Who can join
18 and older, any sex, with Spinal Cord Injury. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
The primary study outcome measure was the variation mean in the number of episodes of urinary incontinence per 24 hours, maximum cystometric capacity, maximum detrusor pressure and bladder compliance
Time frame: Beginning and 24 weeks of the study
Sponsor's own description
The purpose of this study is to compare the effects of oral oxybutynin and intradetrusor injections of botulinum toxin type A on urodynamic parameters and quality of life in patients with neurogenic detrusor overactivity following spinal cord injury.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT01477736
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Oxybutynin
Trials testing the same drug.
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- NCT03919955 — A Novel Pharmacological Therapy for Obstructive Sleep Apnea · Phase 2 · completed
- NCT01557244 — A Study To Find Out How Fesoterodine Works In Children Aged 6 To 17 Years With Bladder Overactivity Caused By A Neurolog · Phase 3 · completed
- NCT01192568 — Safety and Efficacy Evaluation of Oxybutynin Topical Gel In Children With Neurogenic Bladder · Phase 4 · completed
Other recruiting trials for Spinal Cord Injury
Currently open trials in the same condition.
- NCT07429305 — Combined Tibial Nerve Stimulation and Standing for People With SCI · NA · recruiting
- NCT06410001 — CE-STAND: Cervical Epidural STimulation After Neurologic Damage · Phase 1, PHASE2 · recruiting
- NCT05926596 — Leg Stretching Using an Exoskeleton on Demand for People With Spasticity · NA · recruiting
- NCT06839300 — The International Spinal Cord Injury Blood Biomarker Longitudinal Evaluation (I-SCRIBBLE) Study · recruiting
- NCT07036107 — A Trial on the Clinical and Socioeconomic Impact of Wearable Exoskeletons for Spinal Cord Injury Rehabilitation in the S · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01477736 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centro de Reabilitação e Readaptação Dr. Henrique Santillo
- Last refreshed: 19 November 2011
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01477736.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing