Dexamethasone Intravitreal Implant for Treatment of Macular Edema After Plaque Radiotherapy of Uveal Melanoma

NCT01471054 Phase 2 TERMINATED Results posted

To evaluate the safety and efficacy of dexamethasone intravitreal implant (Ozurdex) and compare it with safety and efficacy of intravitreal bevacizumab in eyes with macular edema after plaque radiotherapy of uveal melanoma.

Details

Lead sponsor	Arman Mashayekhi
Phase	Phase 2
Status	TERMINATED
Enrolment	6
Start date	2014-04
Completion	2015-07

Conditions

• Macular Edema
• Cystoid Macular Edema
• Uveal Melanoma
• Radiation Maculopathy
• Radiation Retinopathy

Interventions

• Ozurdex
• Bevacizumab

Primary outcomes

• Number of Participants for Whom Study Eye Showed >=2 Lines of Improvement in Best-corrected Visual Acuity — At 12 months
  The number of participants that developed 2 or more lines of visual acuity improvement in the study eye. Visual acuity was measured with Snellen eye chart placed 10 feet away from the patient.

Countries

United States