NCT01469481 is a Phase 1 clinical trial of PF-04991532 in Healthy, sponsored by Pfizer.

Who is sponsoring NCT01469481?

NCT01469481 is sponsored by Pfizer.

What drugs are being tested in NCT01469481?

Interventions in NCT01469481: PF-04991532.

Is NCT01469481 still recruiting?

NCT01469481 is currently completed. Last updated 27 January 2012.

Last reviewed 2012-01-27 · How we verify

NCT01469481

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

An Open Label, Single-Period, Phase 1 Study To Evaluate The Pharmacokinetics, Excretion, Mass Balance And Metabolism Of [14c]-PF-04991532 In Healthy Adult Male Subjects

Completed Phase 1 Last updated 27 January 2012

What this trial tests

Phase 1 trial testing PF-04991532 in Healthy in 6 participants. Completed in 1 November 2011.

Timeline

1 November 2011

Primary endpoint
1 November 2011

1 November 2011

Quick facts

Lead sponsor	Pfizer
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	basic science
Enrollment	6
Start date	1 November 2011
Primary completion	1 November 2011
Estimated completion	1 November 2011
Sites	1 location across United States

Drugs / interventions tested

PF-04991532 — full drug profile →

Conditions studied

Healthy — all drugs for Healthy →

Sponsor

Pfizer — full company profile →

Who can join

Adults 18 to 55, male only, with Healthy. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Mass Balance: Urinary and fecal excretion of radioactivity over time expressed as a percentage of the total radioactive dose administered.
Time frame: 0-168 hrs
Metabolic Profiling/identification and determination of relative abundance of PF-04991532 and the metabolites of PF-04991532 in plasma, urine, and feces.
Time frame: 0-168 hrs
radioactivity AUC
Time frame: 0-168 hrs
plasma PF-04991532 AUC
Time frame: 0-168 hrs
radioactivity Cmax
Time frame: 0-168 hrs
plasma PF-04991532 Cmax
Time frame: 0-168 hrs

Sponsor's own description

The purpose of this study is to evaluate the excretion balance, metabolic profile and the routes of excretion of \[14C\]PF-04991532 in healthy adult male subjects.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

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Other Pfizer trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01469481 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Pfizer
Last refreshed: 27 January 2012

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01469481.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing