Metformin Plus EE30µg-drospirenone and Weight Loss- Impact on Endothelial Function and hsCRP Levels in PCOS

NCT01459445 NA UNKNOWN

The purpose of this study is to assess the effects of ethinylestradiol 30µg-drospirenone combined with metformin and weight loss by means of dietary intervention on the indices of endothelial dysfunction (i.e. flow-mediated dilation and serum endothelin-1), serum hsCRP,lipids,insulin resistance and body composition in young women with PCOS.

Details

Lead sponsor	Iuliu Hatieganu University of Medicine and Pharmacy
Phase	NA
Status	UNKNOWN
Enrolment	26
Start date	2011-02
Completion	2012-01

Conditions

• Polycystic Ovary Syndrome
• Endothelial Dysfunction

Interventions

• Metformin, Ethinylestradiol 30µg-Drospirenone

Primary outcomes

• flow-mediated dilation — six months

Countries

Romania