The Impact of Intermittent Preventive Malaria Treatment With Artemisinin Combination Therapy (ACT) on Hemoglobin, Malaria, Schistosomiasis, and School Attention Among Primary Schoolchildren in the Kassena-Nankana Districts, Ghana (ACTIPT)

NCT01459146 Phase 4 UNKNOWN

The purpose of this study is to determine if Artemisinin-based Combination Therapy, ACT,(artemether-lumefantrine) used as intermittent preventive treatment (IPT) alone or in combination with praziquantel, will have any effects on anemia, malaria, schistosomiasis and school sustained attention and concentration.

Details

Lead sponsor	Navrongo Health Research Centre, Ghana
Phase	Phase 4
Status	UNKNOWN
Enrolment	345
Start date	2010-12
Completion	2012-11

Conditions

• Malaria
• Schistosomiasis
• Helminthiasis
• Anemia
• Change in Sustained Attention

Interventions

• Artemether-lumefantrine combination plus albendazole
• Artemether-lumefantrine plus Praziquantel plus Albendazole
• Albendazole plus Praziquantel

Primary outcomes

• Prevalence and density of malaria parasites, determined by microscopy, as a measure of efficacy — Day 28 post intervention
  Change from baseline of prevalence and density of malaria parasitemia 28 days post interventions

Countries

Ghana